Catherine O'Hara was 57 in Frankenweenie when she played the character 'Mrs. Frankenstein / Weird Girl / Gym Teacher (voice)'.
That was over 12 years ago in 2012.
Today she is 70, and has starred in 73 movies in total, 12 of those since Frankenweenie was released.
In Frankenweenie, I think Catherine O'Hara looks: