Dan Castellaneta was 27 in Nothing in Common when he played the character 'Brian'.
That was over 38 years ago in 1986.
This was his first recorded movie acting credit (although may not technically be his first actual acting role).
Today he is 66, and has starred in 67 movies in total, 64 of those since Nothing in Common was released.
In Nothing in Common, I think Dan Castellaneta looks: