Tress MacNeille was 56 in Futurama: Into the Wild Green Yonder when she played the character 'Fanny / Michael's Wife / Boobs Vanderbilt / Dixie / Linda / Petunia / Ruth Ginsberg's Head / Mom (voice)'.
That was over 15 years ago in 2009.
Today she is 72, and has starred in 138 movies in total, 28 of those since Futurama: Into the Wild Green Yonder was released.
In Futurama: Into the Wild Green Yonder, I think Tress MacNeille looks: