Reese Witherspoon was 40 in A Wrinkle in Time when she played the character 'Mrs. Whatsit'.
That was over 6 years ago in 2018.
Today she is 48, and has starred in 61 movies in total, 8 of those since A Wrinkle in Time was released.
In A Wrinkle in Time, I think Reese Witherspoon looks: