Neil Patrick Harris was 36 in Cats & Dogs: The Revenge of Kitty Galore when he played the character 'Lou (voice)'.
That was over 14 years ago in 2010.
Today he is 50, and has starred in 79 movies in total, 32 of those since Cats & Dogs: The Revenge of Kitty Galore was released.
In Cats & Dogs: The Revenge of Kitty Galore, I think Neil Patrick Harris looks: