Sasha Alexander was 22 in Visceral Matter when she played the character 'Karen Chambers'.
That was over 27 years ago in 1997.
This was her first recorded movie acting credit (although may not technically be her first actual acting role).
Today she is 51, and has starred in 17 movies in total, 16 of those since Visceral Matter was released.
In Visceral Matter, I think Sasha Alexander looks: