That was over 41 years ago in 1980.
Today she is 46, and has starred in 68 movies in total, 67 since Altered States was released.
In Altered States, I think Drew Barrymore looks:
Altered States scores 6.7 out of 10 on The Movie Database.
Drew Barrymore's first acting role was as 'Margaret Jessup' in Altered States, released in 1980 when she was 5.